DGPIP T 4.5

‘Antibiotics’ class drugs. The medication DGPIP T 4.5 gm injectable falls into the ‘Antibiotics’ class of drugs and is primarily prescribed for various bacterial infections. DGPIP T 4.5 gm injectable is primarily prescribed for intra-abdominal infections, diabetic foot infections, uterine infections, urinary tract infections and both hospital acquired and ventilator associated pneumonia. A bacterial infection occurs when bacteria that have the ability to threaten the human body multiply in any site or any part of the body.

In this DGPIP T 4.5 gm injectable, two medications are included:

Tazobactam, also referred to as a beta lactamase inhibitor and penicillin, is an antibiotic. Piperacillin is a member of the penicillin antibiotics class. Both gram positive and gram negative aerobic and anaerobic bacteria can be killed by it. By attaching itself to the penicillin-binding proteins with the bacterial cell wall, piperacillin prevents the production of the cell wall.

An example of a beta-lactamase inhibitor is tazobactam. Bacteria generate an enzyme known as beta-lactamase to make bacteria multi-resistant against different varieties of drugs that belong to the -lactam group of antibiotics, which is the basis of penicillins and cephalosporins. The role of tazobactam is to inhibit a particular group of microorganisms that secrete the beta-lactamase enzyme to keep various different antibiotics that other groups of micro-organism produces not to get dismantled. With respect to DGPIP T 4.5 gm injectable, tazobactam averts the break-down of piperacillin by the germ.

Uses of DGPIP T 4.5 gm injection

• It is used to treat intra abdominal infection by targeting the bacteria.
• Used in respiratory infections such as pneumonia
• Used for complicated skin and tissue infections, including surgical wounds and diabetic foot infections.
• Used to treat urinary tract infections.
• Used to treat infections in women, including pelvic inflammatory disease and endometritis.

How to use DGPIP T 4.5 gm injectable?

It is administered by a doctor and you can also check the label for directions. Always check the injection with a doctor and never use it on your own, consulting with your healthcare professional.

Side effects of DGPIP T 4.5 gm injectable

• Nausea
• Vomiting
• Diarrhoea
• Stomach pain
• Constipation

Storage

Keep in a cool temperature and keep away from direct sunlight.

What if I take an overdose of DGPIP T 4.5 gm injection?

An overdose would not be possible to take since the injections are done by health care workers. If you develop any of the above symptoms, you need to tell health care worker.

Interaction

Interaction with Drugs

• Heparin
• Vancomycin

Interaction with Diseases

Patients with kidney diseases, bleeding problems, fitting or convulsions, diseases relating to the heart, liver or lungs, as also other serious conditions that could be relevant, must check with their physician beforehand.

Interaction with Food

No Interaction

Interaction with Beverages

Avoid Alcohol

For Pregnant Women

It can be used, but under the supervision of a healthcare professional.

For breastfeeding women

Consult a healthcare provider first.

Lifestyle:

• Include fibre enriched food in your diet
• Take probiotics so they can be easily digested by your gut bacteria
• Don’t take stress and eat healthy food.
• Drink plenty of fluid
• Take plenty of sleep and exercise regularly.

Habit Forming

No

Class of Drug

Antibiotic Combination

FAQs

Can Piperacillin & Tazobactam interact with other medicines?

Yes. It can interact with certain medications including blood thinners, methotrexate and certain medications that can affect kidney function.

Should I complete the full course of treatment?

Yes. It’s important to finish the entire course of treatment as prescribed, even if you begin to feel better, to ensure that the infection is fully eradicated and to prevent antibiotic resistance or relapse.

How should Piperacillin & Tazobactam Injection be stored?

Store the injection according to the manufacturer’s instructions. Hospitals generally store the medicine under specified conditions to ensure it remains effective and to maintain its quality.

Can this medicine be used after surgery?

Yes, Piperacillin & Tazobactam may be prescribed to treat and prevent specific bacterial infections after a surgical procedure, at the treating doctor’s discretion.

Does Piperacillin & Tazobactam require a prescription?

Yes. Piperacillin 4 gm & Tazobactam 0.5 gm Injection is an antibiotic which requires a prescription, and must only be taken under the supervision of a licensed health care professional.

Can diabetic patients receive Piperacillin & Tazobactam Injection?

Yes, individuals with diabetes can receive Piperacillin & Tazobactam Injection when prescribed by a healthcare professional. Blood sugar levels and their overall health need to be carefully monitored during the course of treatment, particularly in those hospitalized.

Why is Tazobactam combined with Piperacillin?

Tazobactam is combined with Piperacillin because it inactivates certain bacterial enzymes (known as beta-lactamases) that could otherwise degrade the antibiotic. The combined medication has an expanded range of antibacterial activity and enhances efficacy against a wider spectrum of sensitive bacteria.